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Attribute
Research Imaging & Microscopy

cryoSPARC

Structura Biotechnology
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CategoryResearch Imaging & Microscopy
CompanyStructura Biotechnology
PriceFree for academic research / Paid commercial license
StatusStatus not confirmed
AvailabilityAvailable via Structura Biotechnology portal
Last checked20/09/2026
FeaturesUltra-fast GPU-accelerated algorithms for ab-initio 3D reconstruction, 3D Variability Analysis (3DVA) resolving continuous macromolecular motions and conformational landscapes, Live processing during automated microscope data collection sessions, Modern web-based graphical interface with multi-user project management
Entry typeScientific Platform
Access modeFree Academic / Paid Commercial
AI roleAlgorithmic Optimization & 3D Variability
Input dataNot recorded
Output dataNot recorded
Licence conditionsProprietary / Free Academic License
Commercial eligibilityFree for academic non-profit research; paid license for commercial industry use
Compute requirementsLinux server with NVIDIA GPUs (RTX 4090, A100, or H100)
ValidationNot recorded
TypeCryo-EM processing platform
Intended useNot recorded
CompatibilityNot recorded
ManufacturerStructura Biotechnology Inc.
Biological applicationStructural biology, drug-target complex resolution, and conformational dynamics
Research workflowAutomated pipeline from raw camera frames to sharpened 3D electron density maps
Evidence levelWidely published across Nature, Science, and Cell structure determinations
Integration evidencehttps://cryosparc.com
Laboratory handoffDelivers 3D maps directly to molecular modeling and drug docking pipelines