TOTAL ACTIVE BUDGET
$3.85M
Across 6 active requests
VERIFIED SPONSORS
14
Pharma & Biotech leaders
AVG. MATCH TIME
9 Days
From submission to contract
CONFIDENTIALITY
Mutual NDA
Automated escrow & legal flow
RFP-2026-089Open

De novo Macrocyclic Peptide Design against KRAS G12D

Global Top-10 Pharma (Oncology Division) · Enterprise Pharma

Seeking machine learning partners to design high-affinity macrocyclic peptides targeting the switch-II pocket of KRAS G12D with sub-nanomolar affinity and high membrane permeability.

Generative DiffusionMolecular DynamicsPermeability PredictionRFdiffusion / Chai-1
BUDGET$350,000 - $500,000
DEADLINE2026-10-15
RFP-2026-104Closing Soon

Predicting Off-Target Toxicity via Spatial Transcriptomics GNNs

Boston Flagship Biotech · Clinical Stage Biotech

Development of graph neural network models combining 10x Visium spatial transcriptomics with chemical fingerprints to forecast organ-specific off-target liabilities in preclinical animal cohorts.

Graph Neural NetworksSpatial OmicsTox21 / DeepChemPyTorch Geometric
BUDGET$180,000 - $250,000
DEADLINE2026-10-01
RFP-2026-112Open

Cryo-EM Automated Density Map Fitting with Deep Generative Models

Cambridge Structural AI Institute · Academic / Consortium

Open-source benchmark and model pipeline to fit atomic coordinates into low-resolution (3.5 - 5.0 Å) Cryo-EM single-particle reconstructions with high confidence and automated sidechain placement.

Cryo-EM Map ProcessingAlphaFold 3 CoordinatesPyMOL / ChimeraX APIOpen-Source (MIT)
BUDGET$120,000 - $180,000
DEADLINE2026-11-20
RFP-2026-135Open

High-Throughput Virtual Screening of 10B Ultra-Large Chemical Library

Swiss Oncology Venture · Series B Biotech

Ultra-fast GPU-accelerated molecular docking and ML rescoring across the complete Enamine REAL 10-billion compound space against 3 novel epigenetic targets.

DiffDock / Uni-MolGPU Cluster OrchestrationEnamine REAL SpaceADMET Profiling
BUDGET$650,000 - $900,000
DEADLINE2026-10-30
RFP-2026-141Open

Multi-Specific Antibody Affinity Maturation using Generative Protein Models

Bay Area Immuno-Oncology Lab · Enterprise Biotech

Optimize binding affinity of a bispecific T-cell engager (BiTE) against HER2/CD3 while reducing non-specific liver clearance and viscosity at high concentration formulations.

ESM-3 / AntiFoldSurface Charge ModelingImmunogenicity De-riskingWet-lab Validation Cohort
BUDGET$500,000 - $750,000
DEADLINE2026-11-05
RFP-2026-152Open

Foundational RNA Secondary Structure Prediction with Pseudoknots

Nordic RNA Therapeutics Hub · Research Foundation

Benchmarking and novel deep learning architectures for secondary and tertiary structure prediction of synthetic circular RNAs and mRNA vaccine constructs.

RNA Structure PredictionViennaRNA / EternaFoldTransformer ArchitecturesRibosome Profiling
BUDGET$200,000 - $300,000
DEADLINE2026-12-01