ProGen 2

Biological & Workflow Fit

Biological Application

Enzyme engineering, antibody optimization, and zero-shot fitness prediction

Research Workflow

Generate sequence variants with high predicted stability and activity

Compute & Hardware

1x GPU (>= 16GB VRAM) for inference

Licensing & Academic Use

BSD-3-Clause

Documented Evidence

View validation publication / source ↗

Use this citation format when referencing ProGen 2 in scientific publications and benchmark papers.

@software{progen_2_2026,
  title = {{ProGen 2}},
  author = {{Salesforce AI Research}},
  year = {2026},
  url = {https://github.com/salesforce/progen},
  note = {Indexed on aibioatlas - AI for Biology and Drug Discovery}
}