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将生物大模型、对接计算引擎与组学管线并排横向对比。按获取方式、硬件开销及细分领域灵活筛选，在一分钟内得出客观可辩护的技术选型方案。
| 技术参数指标 | ＋ 添加工具 | |||
|---|---|---|---|---|
| Category | Biological AI Models | Biological AI Models | Biological AI Models | — |
| Subcategory | Protein Structure | Protein Design | Protein Design | — |
| Company | ColabFold contributors | RosettaCommons / Baker Lab | ProteinMPNN authors | — |
| Access mode | Public code / project terms | Public code | Public code | — |
| Licence conditions | Review the linked release, model weights, datasets and service terms separately | Check repository licence and checkpoint terms | Check code, dependencies and model terms | — |
| Compute requirements | Consult linked installation guidance; workload dependent | Version and workload dependent; not independently benchmarked | Version and workload dependent; not independently benchmarked | — |
| Biological application | 未明确记录 | 未明确记录 | 未明确记录 | — |
| Research workflow | 未明确记录 | 未明确记录 | 未明确记录 | — |
| Evidence level | Project or provider documentation; no local performance benchmark | Project documentation; no local benchmark | Project documentation; no local benchmark | — |
| Commercial eligibility | Not independently confirmed | Confirm exact code, weights and data terms | Confirm exact code, weights and data terms | — |
| Price | See project terms; compute costs may apply | See access and licence terms | See access and licence terms | — |
| Availability ⓘ | See project access and maintenance status | Public code | Public code | — |
| Features | Accessible notebooks and local workflows for protein folding, Input: Protein sequences and selected notebook or model, Output: Predicted structures and model-specific confidence outputs | Diffusion-based protein backbone design, Documented research workflow | Protein sequence design from structure, Documented research workflow | — |
| Entry type | Research software / model | Research software / model | Research software / model | — |
| AI role | Workflow wrapper for folding models | Machine-learning software | Machine-learning software | — |
| Input data | Protein sequences and selected notebook or model | Design constraints and optional structural motifs | Protein backbone structures | — |
| Output data | Predicted structures and model-specific confidence outputs | Designed protein backbones | Candidate amino-acid sequences | — |
| Validation | Evaluate on representative data; no clinical suitability established | Evaluate on representative held-out data | Evaluate on representative held-out data | — |
| Type | 未明确记录 | 未明确记录 | 未明确记录 | — |
| Intended use | Biological and pharmaceutical research | 未明确记录 | 未明确记录 | — |
| Compatibility | 未明确记录 | 未明确记录 | 未明确记录 | — |
| Limitations | A workflow wrapper, not a separate foundation model; hosted resources and underlying model terms vary. | 未明确记录 | 未明确记录 | — |