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Confronta modelli biologici, motori di docking e flussi di calcolo affiancati. Filtra per modello di accesso, impronta di calcolo e categoria per ottenere una tabella decisionale attuabile in meno di un minuto.
| Attributo | Biological Foundation Models RFdiffusion All-Atom (RFdiffusionAA)Institute for Protein Design (Baker Lab)Codice aperto⚡ A100/H100 | ＋ Aggiungi strumento |
|---|---|---|
| Category | Biological Foundation Models | — |
| Subcategory | De Novo Protein Design | — |
| Company | Institute for Protein Design (Baker Lab) | — |
| Access mode | Academic Open Source | — |
| Licence conditions | Open Source for academic research; commercial license required for for-profit use | — |
| Compute requirements | 1x NVIDIA A100 or RTX 4090 GPU (>= 24GB VRAM) | — |
| Biological application | Enzyme active site design, small molecule sensor engineering, and drug receptor design | — |
| Research workflow | Diffusion of protein backbone and sidechains around explicit ligand coordinates | — |
| Evidence level | Peer-reviewed research (Science 2024) | — |
| Commercial eligibility | Commercial licensing available through University of Washington CoMotion | — |
| Price | Free for academic research / Paid commercial license | — |
| Availability ⓘ | Available on GitHub | — |
| Features | De novo design of protein binding pockets around specified small molecules, Co-generation of protein binders with coordinated catalytic ions and cofactors, Full atomic coordinate representation during the reverse diffusion trajectory, Seamless integration with LigandMPNN for sequence design | — |
| Entry type | AI Model / Software | — |
| AI role | De Novo Molecular Diffusion | — |
| Input data | Non registrato | — |
| Output data | Non registrato | — |
| Validation | Non registrato | — |
| Type | Generative all-atom diffusion model | — |
| Intended use | Non registrato | — |
| Compatibility | Non registrato | — |
| Manufacturer | Institute for Protein Design | — |
| Integration evidence | https://github.com/baker-laboratory/rf_diffusion_all_atom | — |
| Laboratory handoff | Designs validated via yeast surface display and biolayer interferometry (BLI) | — |