Missing values mean the catalog has no recorded information. They do not mean a feature is absent.
Entry typeSoftware Library (R / Python)
Access modeOpen Source
AI roleIterative Dimensionality Alignment
Input dataNot recorded
Output dataNot recorded
Licence conditionsGPL-3.0
Commercial eligibilityPermissive open source release
Compute requirementsStandard CPU workstation
ValidationNot recorded
TypeSingle-cell batch integration algorithm
Intended useNot recorded
CompatibilityNot recorded
ManufacturerBroad Institute of MIT and Harvard
Biological applicationCross-tissue cell atlas integration, patient cohort harmonization, and multi-donor studies
Research workflowUncorrected PCA matrix -> Harmony batch alignment -> corrected embedding for clustering and UMAP
Evidence levelPeer-reviewed research (Nature Methods 2019) with thousands of citations
Integration evidencehttps://github.com/immunogenomics/harmony
Laboratory handoffProduces clean cell clusters for cell-type sorting and downstream validation
AvailabilityAvailable on CRAN, PyPI, and GitHub
Price / accessFree Open Source